Search on: SODIUM CHLORIDE SYMPORTERS 
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Descriptor English:   Sodium Chloride Symporters 
Descriptor Spanish:   Simportadores de Cloruro de Sódio 
Descriptor Portuguese:   Simportadores de Cloreto de Sódio 
Tree Number:   D12.776.157.530.450.625.374
Definition English:   A subclass of symporters found in KIDNEY TUBULES, DISTAL that are the major pathway for salt resorption. Inhibition of these symporters by BENZOTHIADIAZINES is the basis of action of some DIURETICS. 
Indexing Annotation English:   coordinate with DIURETICS if pertinent
Entry Combination - descr/qualif English:   Sodium Chloride Symporters/antagonists & inhibitors use Sodium Chloride Symporter Inhibitors
 
See Related English:   Gitelman Syndrome
 
History Note English:   2006(1984); for SODIUM-CHLORIDE COTRANSPORTER use SYMPORTERS (NM) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DU diagnostic use
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Record Number:   50908 
Unique Identifier:   D049992 

Occurrence in VHL: 		 

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